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Greys Anatomy - S05E20 - Sweet Surrender.mp4 Plot Summary: Izzie bites off more than she can chew on her first day of chemotherapy, Mark and Derek are forced to work on the same patient, Meredith's plans for a simple wedding take a turn, and Karev finds himself split between worry over Izzie and excelling as a resident. Release Date: 2009-04-23 Directors: Tony Phelan Writers: Shonda Rhimes, Sonay Hoffman, Peter Nowalk Starcast: Ellen Pompeo, Sandra Oh, Katherine Heigl

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